規(guī)格:50μL/100μL
貨號:PN0170
價格:1350元/50μL;2200元/100 μL
全稱 | Bromodeoxyuridine |
別名 | Bromodeoxyuridine, Bromodeoxyuridine,5-Bromo-2′-deoxyuridine; 5-BrdU, Proliferation Marker; 5-Bromo-2-deoxyUridine |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
交叉反應 | All species |
產品應用 | IHC/IF : 1: 100-1: 500 |
細胞定位 | 細胞核 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse BrdU |
亞 型 | IgG1,k |
純化方法 | Affinity purification |
緩 沖 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存條件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Bromodeoxyuridine (5-bromo-2'-deoxyuridine, BrdU, BUdR, BrdUrd) is a synthetic nucleoside that is an analog of thymidine. It can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. As such, BrdU is used for birth dating and monitoring cell proliferation. BrdU is a toxic and mutagenic substance. It triggers cell death, the formation of teratomas, alters DNA stability, lengthens the cell cycle, and has mitogenic, transcriptional and translational effects on cells that incorporate it.