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細(xì)胞骨架
細(xì)胞骨架

Anti-Collagen I Rabbit pAb

規(guī)格:50μL/100μL

貨號(hào):PN0200

價(jià)格:1350元/50μL;2200元/100 μL

產(chǎn)品特性



全稱

Collagen alpha-1(I) chain

別名

COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain

抗體來源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

Human;Mouse;Rat

產(chǎn)品應(yīng)用

WB 1:500-1:1000

IHC/IF 1:500-1:1500

理論/實(shí)際分子量

139kDa / 120-140 kDa/200-250 kDa

細(xì)胞定位

細(xì)胞質(zhì) 細(xì)胞外基質(zhì)

性    狀

Liquid

濃    度


免 疫 原

KLH conjugated Synthetic peptide corresponding to Human COL1A1

亞    型

IgG

純化方法

Affinity-chromatography

Uniprot ID

P02452

緩 沖 液

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

保存條件

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

    This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.