規(guī)格:50μL/100μL
貨號(hào):PN0200
價(jià)格:1350元/50μL;2200元/100 μL
全稱 | Collagen alpha-1(I) chain |
別名 | COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human;Mouse;Rat |
產(chǎn)品應(yīng)用 | WB 1:500-1:1000 IHC/IF 1:500-1:1500 |
理論/實(shí)際分子量 | 139kDa / 120-140 kDa/200-250 kDa |
細(xì)胞定位 | 細(xì)胞質(zhì) 細(xì)胞外基質(zhì) |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Human COL1A1 |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
Uniprot ID | P02452 |
緩 沖 液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.